The antibody–drug conjugate SHR-A1904 for targeting CLDN18.2 in advanced gastric or gastroesophageal junction cancer: a phase 1 trial

已完结 20 由 karry 发布于 2025/7/26 11:09:57

DOI:10.1038/s41591-025-03781-w
作者：Dan-Yun Ruan, Hao-Xiang Wu, Su-Xia Luo, Wen-Wen Huang, Xin-Jun Liang, Zuo-Xing Niu, Qi Dang, Hong-Li Li, Zhan-Yu Pan, Hong-Xia Lu, Yan-Qiao Zhang, Xing-Ya Li, Xiu-Ying Xiao, Shi-Rong Cai, Yu-Gang Dong
文献类型：期刊论文
补充材料：只需要正文

Nature

Abstract：Claudin-18 isoform 2 (CLDN18.2), a tight junction protein expressed in non-malignant gastric epithelium and exposed on tumor cell surface during malignant transformation, is a promising ther

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