NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity.

已完结 20 由南鲨发布于 2025/7/25 11:26:38

DOI:10.1038/s41586-025-09303-5
作者：Janna Heide,Agnes J Bilecz,Samarjit Patnaik,Maria Francesca Allega,Leonhard Donle,Kaiting Yang,Ethan Teich,Yan Li,Qiaoshan Lin,Ke Kong,Li Liu,Tae Gyun Yang,Ken Chih-Chien Cheng,Jonathan H Shrimp,Quinl
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Abstract：Cancer-associated fibroblasts (CAFs) have a pivotal cancer-supportive role, yet CAF-targeted therapies are lacking1,2. Here, using spatial transcriptomics and single-cell RNA sequencing, we

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