Discovery of AB801, a Potent and Selective Inhibitor of AXL Receptor Tyrosine Kinase for Use in Cancer Therapy.

已完结 20 由小小发布于 2025/7/31 9:22:05

DOI:10.1021/acs.jmedchem.5c00239
作者：Dillon H Miles,Manjunath Lamani,Srinivas Reddy Paladugu,Shiwei Qu,Corinne N Foley,Ehesan U Sharif,Joice Thomas,Pradeep Nareddy,Joel W Beatty,Balint Gal,Guiling Zhao,Rebecca Grange,Stefan G Shaqfeh,Ada
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：AXL receptor tyrosine kinase (AXL), a transmembrane protein highly expressed in a variety of cancers, has been implicated in the development of resistance to various forms of therapy and poo

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