Enhancing the specific activity of 3α-hydroxysteroid dehydrogenase through cross-regional combinatorial mutagenesis

已完结 20 由龙的心发布于 2025/7/30 17:56:59

DOI:10.1016/j.ijbiomac.2024.137014
作者：Siqi Ma , Musen Li , Shengheng Yan , Yi Wang , Binju Wang , Wei Luo
文献类型：期刊论文
补充材料：只需要正文

Elsevier

Abstract：3α-Hydroxysteroid dehydrogenase (3α-HSD) from Comamonas testosteroni is widely used in clinical settings to measure serum total bile acid levels. However, its low enzymatic activity leads to

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