B cells drive CCR5+CD4+ tissue-resident memory T cell cytotoxicity via IL-15Rα-IL-15 signaling in primary biliary cholangitis

已完结 20 由 000 发布于 2025/8/1 22:36:06

DOI:10.1016/j.jhep.2025.06.037
作者：Xiting Pu, Yuyang Liu, Zhuwan Lyu, Yujie Zhou, Yudong Zhao, Bingyuan Huang, Qiyun Xia, Yi Wu, Jun Qian, Ruqi Tang, Min Lian, Xiong Ma, Zhengrui You
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1016/j.jhep.2025.06.037

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Abstract：Background AimsIL-15Rα mediates immune responses by binding and trans-presenting IL-15 to tissue-resident memory T (TRM) cells, enabling sustained activation. Given the pivotal role of IL-1

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