Improved identification of tumor-specific TCRs from circulating lymphocytes using autologous colorectal tumor organoids

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DOI:10.1016/j.canlet.2025.218036
作者：Lisha Ma , Xiya Wang , Qianjing Zhang , Zhaoya Gao , Xiangwen Ji , Zhilang Li , Yixian Li , Pengchong Zhang , Xuan Che , Yun Sun , Yun Bai , Hong
文献类型：期刊论文
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Elsevier

Abstract：The identification of effective T cell receptors (TCRs) with specific reactivity against tumor cells is critical for the efficacy of TCR-engineered T cell therapy. However, different approac

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