Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity

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DOI:10.1101/2024.03.14.585062
作者：Xin Luo, Kathleen M. McAndrews, Kent A. Arian, Sami J. Morse, Viktoria Boeker, Shreyasee V. Kumbhar, Yingying Hu, Krishnan K. Mahadevan, Kaira A. Church, Sriram Chitta, Nicolas T. Ryujin, Janine Hense
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Abstract：mRNA incorporated in lipid nanoparticles (LNPs) became a new class of vaccine modality for induction of immunity against COVID-19 and ushered in a new era in vaccine development. Here, we re

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