DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2–p53 Inhibitor

已完结 20 由 phyjun 发布于 2025/8/3 23:31:31

DOI:10.1021/acsmedchemlett.3c00117
作者：Anthony P. Silvestri*,?Qi Zhang,?Yan Ping,?Erik W. Muir,?Jingsi Zhao,?Sai Kumar Chakka,?Gaonan Wang,?Walter M. Bray,?Wenhua Chen,?Jennifer L. Fribourgh,?Sarvind Tripathi,?Yunyun He,?Seth M. Rubin,?Ale
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Synthetic macrocyclic peptides are an emerging molecular class for both targeting intracellular protein–protein interactions (PPIs) and providing an oral modality for drug targets typically

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