Design and application of the transformer base editor in mammalian cells and mice

已完结 10 由 rui 发布于 2025/8/7 13:35:41

DOI:10.1038/s41596-023-00877-w
作者：Wenyan Han,?Bao-Qing Gao,?Junjie Zhu,?Zongxing He,?Jianfeng Li,?Li Yang,?Jia Chen
文献类型：期刊论文
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Nature

Abstract：Fusing apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like cytidine deaminase with catalytically impaired Cas proteins (e.g., nCas9 or dCas9) provides a novel gene-editing techn

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