Single-nucleus interrogation of primate small intestinal aging reveals NCoR1 decline as a conserved feature that is reversed by metformin

已完结 10 由 nana 发布于 2026/7/31 11:40:55

DOI:10.1038/s43587-026-01131-0
作者：Jingyi Li, Xiaoyong Lu, Tianhong Tong, Xin Zhou, Baohu Zhang, Xiaoyan Sun, Bing Zhao, Gang Xu, Jinjiang Yang, Yanling Fan, Jianli Hu, Haoteng Yan
文献类型：期刊论文
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Nature

Abstract：How the small intestine ages at the cellular and molecular level has been unclear. Here we profile single nuclei from young and aged primate small intestine and find that aging brings barrie

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