ALKBH1 drives tumorigenesis and drug resistance via tRNA decoding reprogramming and codon-biased translation.

已完结 20 由 BLOOD 发布于 2025/8/15 12:49:20

DOI:10.1158/2159-8290.cd-24-1043
作者：Chao Shen,Yuan Che,Keren Zhou,Kitty Wang,Wei Li,Diyuan Xue,Tong Wu,Lu Yang,Meiling Chen,Yue Sheng,Chengwan Zhang,Sean Robinson,Huiying Chen,Lillian Sau,Zhenhua Chen,Mark Wunderlich,Li Han,Tingting Tan
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1158/2159-8290.cd-24-1043

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Abstract：Cancer cells utilize codon-biased translation to fuel tumorigenesis and drug resistance, but underlying mechanisms remain poorly understood. Here, we show ALKBH1 is overexpressed in acute my

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