Highly Selective N-Alkylation of Pyrazoles: Crystal Structure Evidence for Attractive Interactions

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DOI:10.1021/acs.joc.2c00980
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1021/acs.joc.2c00980

American Chemical Society (ACS)

Abstract：Inspired by crystal structures, we designed and achieved a catalyst-free Michael reaction for the preparation of an N1-alkyl pyrazole in a high yield (90%) with excellent regioselectivity (N

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