The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex

已完结 10 由 hfpf 发布于 2025/6/28 8:22:05

DOI:10.1016/j.molcel.2024.04.007
作者：Dimitrios Papadopoulos, Stefanie Anh Ha, Daniel Fleischhauer, Leonie Uhl, Timothy J. Russell, Ivan Mikicic, Katharina Schneider, Annika Brem, Omkar Rajendra Valanju, Giacomo Cossa, Peter Gallant, Chri
文献类型：期刊论文
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Elsevier

Abstract：The MYCN oncoprotein binds active promoters in a heterodimer with its partner protein MAX. MYCN also interacts with the nuclear exosome, a 3′-5′ exoribonuclease complex, suggesting a functio

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