Using enzymes to tame nitrogen-centred radicals for enantioselective hydroamination

待确认 10 由丫丫发布于 2026/7/30 17:33:22

DOI:10.1038/s41557-022-01083-z
作者：Yuxuan Ye,?Jingzhe Cao,?Daniel G. Oblinsky,?Deeptak Verma,?Christopher K. Prier,?Gregory D. Scholes,?Todd K. Hyster
文献类型：期刊论文
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Nature

Abstract：The formation of C–N bonds—of great importance to the pharmaceutical industry—can be facilitated enzymatically using nucleophilic and nitrene transfer mechanisms. However, neither natural no

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