Patient-derived ovarian cancer organoids as platforms for predicting platinum resistance and screening tumor stem cell inhibitors

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DOI:10.1016/j.drup.2026.101411
作者：Mingxia Ye ,?Yawen Wu ,?Zexin Chen ,?Qingzhi Zhai ,?Lian Li ,?Zhifeng Yan ,?Mingxia Li ,?Chenglei Gu ,?Wen Yang ,?Shujie Liao ,?Yuanguang Meng
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Abstract：BackgroundOvarian cancer is the deadliest gynecological malignancy, with platinum-based chemotherapy being the standard treatment. However, most patients develop resistance to platinum treat

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