Rational design of an NLRP3 inhibitor with superior efficacy and safety for gout therapy

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DOI:10.1016/j.ejmech.2026.118578
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1016/j.ejmech.2026.118578

Elsevier

Abstract：Gout, driven by urate crystal-induced inflammation, remains a therapeutic challenge due to the limited efficacy and toxicity of current treatments. Targeting the NLRP3 inflammasome, a centra

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