Development of a Scalable Asymmetric Process for the Synthesis of GLYT1 Inhibitor BI 425809 (Iclepertin)

已完结 10 由杨小木发布于 2025/7/6 20:38:45

DOI:10.1021/acs.oprd.2c00373
作者：R. Frutos, Thomas G. Tampone, J. Mulder, Joe J. Gao, J. Sieber, S. Rodriguez, N. Haddad, Katrin Baer, Jack D. Brown, Bing-Shiou Yang, R. Giovannini, Jinhua J. Song, N. Grinberg, Heewon Lee, C. Senanay
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：A robust and scalable synthesis process for BI 425809 (Iclepertin), a GLYT1 inhibitor with potential therapeutic properties for the treatment of central nervous system disorders, was develop

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