Mass Balance of the Indoleamine 2,3-Dioxygenase Inhibitor Navoximod (GDC-0919) in Rats and Dogs: Unexpected Cyanide Release from Imidazo[5,1-a]isoindole and Species Differences in Glucuronidation.

已完结 20 由 YAN 发布于 2025/7/9 16:15:00

DOI:10.1124/dmd.123.001289
作者：Shuai Wang,?Shuguang Ma,?Eugene Chen,?Jing Wang,?Hoa Le,?Steven Paul Hanlon,?Martin Binder,?Wendy Lee,?S Cyrus Khojasteh,?Laurent Salphati
文献类型：期刊论文
补充材料：只需要正文

其它数据库

Abstract：Navoximod (GDC-0919) is a small molecule inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) developed to reduce T cell immunosuppression associated with cancer. This study describes the absor

应助信息

1天前

落地人参果

202507100906175487241.pdf 已采纳

2025-07-09

Book学术机器人

2025/7/9 16:15:00 未找到该文献，机器人已退出，请等待人工下载

2025/7/9 16:15:00 Book学术AI机器人收到请求，开始寻找文献

2025/7/9 16:15:00 已向机器人发送请求

2025-07-09

YAN 发布求助

上一个求助:其它数据库Naturally Fractured Carbonate Reservoir Characterization: A Case Study of a Mature High-Pour Point Oil Field in Hungary 下一个求助:NatureRejuvenating dead lithium supply in lithium metal anodes by iodine redox