Ultrahigh-concentration biologic therapeutics enabled by spray drying with a glassy surfactant excipient

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DOI:10.1126/scitranslmed.adv6427
作者：Carolyn K. Jons,?Alexander N. Prossnitz,?Noah Eckman,?Changxin Dong,?Ashley Utz,?Eric A. Appel
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：Biopharmaceuticals such as peptides and antibodies have become critical to health care. Despite their exceptional potency and specificity, biopharmaceuticals are prone to aggregation, which

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