Engineered Bacteria Manipulate Cysteine Metabolism to Boost Ferroptosis-Based Pancreatic Ductal Adenocarcinoma Therapy

已完结 20 由 knock 发布于 2025/7/21 18:20:42

DOI:10.1002/adma.202412982
作者：Chaoqiang Qiao, Lexuan Wang, Chuting Huang, Qian Jia, Weier Bao, Peilin Guo, Dengxu Tan, Zhuang Chen, Changhong Shi, Zhiping Rao, Ruili Zhang, We
文献类型：期刊论文
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Wiley

Abstract：Cysteine metabolism is a key determinant of the defense against ferroptosis in pancreatic ductal adenocarcinoma (PDAC). Blocking cysteine metabolism may trigger potent ferroptosis in PDAC ce

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