Ligation-recognition triggered RPA-Cas12a cis-cleavage fluorogenic RNA aptamer for one-pot and label-free detection of MicroRNA in breast cancer

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DOI:10.1016/j.bios.2024.117106
作者：Hao Liu ,?Meng-Mei Lv ,?Xiang Li ,?Mei Su ,?Yin-Gang Nie ,?Zhan-Ming Ying
文献类型：期刊论文
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Elsevier

Abstract：“One-pot” assays which combine amplification with CRISPR/Cas12a system are in constant attracted for biosensors development. Herein, we present a one-pot isothermal assay that Ligation-recog

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