Integrative Salt Selection and Formulation Optimization: Perspectives of Disproportionation and Microenvironmental pH Modulation

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DOI:10.1021/acs.molpharmaceut.4c00166
作者：Shikhar Mohan, Yi Li, Kevin Chu, Liliana De La Paz, Diana Sperger, Bing Shi, Chris Foti, Victor Rucker and Chiajen Lai*, 
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：We report a novel utilization of a pH modifier as a disproportionation retardant in a tablet formulation. The drug molecule of interest has significant bioavailability challenges that requir

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