Investigation of the Dissolution Behavior of Diludine in Monosolvents: Solid–Liquid Equilibrium Determination, Model Correlation, and Thermodynamic Analysis

已完结 10 由归！发布于 2025/9/13 18:31:13

DOI:10.1021/acs.jced.5c00370
作者：Yajun Li,?Aoxiang Xu,?Jili Zheng,?Xianhe Deng,?Can Hu,?Jun Zhu* and Kui Wu*,?
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Diludine and its derivatives are important precursors widely employed in the design and synthesis of dihydropyridine calcium channel blocker (CCB) drugs. The solid–liquid-phase equilibrium d

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