GABA-dependent microglial elimination of inhibitory synapses underlies neuronal hyperexcitability in epilepsy

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DOI:10.1038/s41593-025-01979-2
作者：Zhang-Peng Chen, Xiansen Zhao, Suji Wang, Ruolan Cai, Qiangqiang Liu, Haojie Ye, Meng-Ju Wang, Shi-Yu Peng, Wei-Xuan Xue, Yang-Xun Zhang, Wei Li, Hua Tang, Tengfei Huang, Qipeng Zhang, Liang Li, Lixia
文献类型：期刊论文
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Nature

Abstract：Neuronal hyperexcitability is a common pathophysiological feature of many neurological diseases. Neuron–glia interactions underlie this process but the detailed mechanisms remain unclear. He

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