Caltrop-like Small-Molecule Antidotes That Neutralize Unfractionated Heparin and Low-Molecular-Weight Heparin In Vivo

已完结 10 由画舫发布于 2025/9/22 16:47:24

DOI:10.1021/acs.jmedchem.3c02224
作者：Yang Zong, Zhuo Lei, Shang-Bo Yu*, Ling-Yu Zhang, Yan Wu, Ke Feng, Qiao-Yan Qi, Yamin Liu, Yajie Zhu, Peng Guo, Wei Zhou*, Dan-Wei Zhang and Zhan
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Unfractionated heparin (UFH) and low-molecular-weight heparins (LMWHs) are widely applied for surgical procedures and extracorporeal therapies, which, however, suffer bleeding risk. Protamin

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