Erythroid-predominant myelodysplastic neoplasms exhibit a distinct genomic landscape with poor outcomes after venetoclax-based therapy

已完结 10 由糊糊小饼干发布于 2025/9/30 16:29:35

DOI:10.1038/s41375-025-02711-6
作者：Alexandre Bazinet,?Sanam Loghavi,?Yue Wei,?Alex Bataller,?Koji Sasaki,?Naszrin Arani,?Faezeh Darbaniyan,?Kelly Chien,?Danielle Hammond,?Ian Bouligny,?Rashmi Kanagal-Shamanna,?Natthakan Thongon,?Guilin
文献类型：期刊论文
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Springer

Abstract：Erythroid differentiation confers BCL-XL dependence and venetoclax resistance in acute myeloid leukemia (AML). However, whether myelodysplastic neoplasms (MDS) with erythroid predominance (E

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