Scaling up a C–H Borylation: Addressing the Safety Concerns of an Iridium-Catalyzed Process for Multikilo Scale Manufacture

已完结 20 由 LZI 发布于 2025/8/19 19:30:05

DOI:10.1021/acs.oprd.1c00432
作者：Amanda Jane Lyons,?Adam Clarke,?Heidi Fisk,?Bethany Jackson,?Peter R. Moore,?Samantha Oke,?Thomas O. Ronson and Rebecca E. Meadows*,?
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Iridium-catalyzed C–H borylation reactions are a rapid and versatile entry into Suzuki coupling partners, but their inherent safety issues can limit their use in large-scale manufacture. The

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