GZR18, a novel long-acting GLP-1 analog, demonstrated positive in vitro and in vivo pharmacokinetic and pharmacodynamic characteristics in animal models

已完结 20 由木子木发布于 2025/8/19 15:53:28

DOI:10.1016/j.ejphar.2022.175107
作者：Man Zhang , Yining Zhang , Xiaohong Peng , Anshun He , Yue Wang , Ying Deng , Cheng Cui , Fangkai Xue , Bing Wei , Wancai Xing , Yuzhen Qian , Mi
文献类型：期刊论文
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Elsevier

Abstract：GZR18 is a novel analog of glucagon-like peptide-1 (GLP-1). This study evaluates the pharmacology, pharmacokinetics, and efficacy of GZR18, and its potential for the treatment of Type 2 diab

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