Formation of a Disulfide Bridge on the Resin during Solid-Phase Synthesis of Terlipressin: Influence of the Boc-Protected and Free N-Terminal Amino Group

已完结 20 由 ASshen 发布于 2025/8/26 15:13:16

DOI:10.1021/acs.oprd.3c00142
作者：Dmitry Avdeev*,?Michael V. Ovchinnikov,?Michael G. Medvedev,?Alexander S. Molokoedov and Maria V. Sidorova,?
文献类型：期刊论文
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Abstract：An industry-ready approach for the synthesis of terlipressin is developed: the entire peptide chain assembly and subsequent disulfide bond closure are carried out on a polymeric carrier with

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