Reprogramming CD8+ T-cell branched N-glycosylation limits exhaustion, enhancing cytotoxicity and tumor killing.

已完结 20 由 123 发布于 2025/9/3 9:39:29

DOI:10.1158/2326-6066.CIR-25-0313
作者：Catarina M Azevedo,?Bingxian Xie,?William G Gunn,?Ronal M Peralta,?Carolina S Dantas,?Henrique Fernandes-Mendes,?Supriya Joshi,?Victoria Dean,?Pedro Almeida,?Drew Wilfahrt,?Nuno Mendes,?Julian López
文献类型：期刊论文
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American Association for Cancer Research (AACR)

Abstract：T-cell therapies have transformed cancer treatment. Although surface glycans have been shown to play critical roles in regulating T-cell development and function, whether and how the glycome

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