Toward a Complete Elucidation of the Primary Structure-Activity in Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers for In Vivo Delivery of Luc-mRNA.

已完结 10 由在路上发布于 2025/4/21 9:48:51

DOI:10.1021/acs.biomac.4c01599
作者：Dipankar Sahoo,?Elena N Atochina-Vasserman,?Juncheng Lu,?Devendra S Maurya,?Nathan Ona,?Jessica A Vasserman,?Houping Ni,?Sydni Berkihiser,?Wook-Jin Park,?Drew Weissman,?Virgil Percec
文献类型：期刊论文
补充材料：只需要正文

American Chemical Society (ACS)

Abstract：Four-component lipid nanoparticles (LNPs) and viral vectors are key for mRNA vaccine and therapeutics delivery. LNPs contain ionizable lipids, phospholipids, cholesterol, and polyethylene gl

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