Efficient non-viral immune cell engineering using circular single-stranded DNA-mediated genomic integration

已完结 10 由 Vince 发布于 2026/7/6 13:35:45

DOI:10.1038/s41587-024-02504-9
作者：Keqiang Xie, Jakob Starzyk, Ishita Majumdar, Jiao Wang, Katerina Rincones, Thao Tran, Danna Lee, Sarah Niemi, John Famiglietti, Bernhard Suter, Richar
文献类型：期刊论文
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Nature

Abstract：The use of adeno-associated viruses (AAVs) as donors for homology-directed repair (HDR)-mediated genome engineering is limited by safety issues, manufacturing constraints and restricted pack

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