Improving the safety of lipid nanoparticle-based DNA delivery for extended gene expression

已取消 10 由 hanacc 发布于 2025/4/25 17:16:25

DOI:10.1038/s41587-025-02600-4
文献类型：期刊论文
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Nature

Abstract：DNA delivery using lipid nanoparticles results in severe toxicity in mice. However, we find that the incorporation of endogenous anti-inflammatory lipids into the lipid nanoparticles mitigat

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