Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders

已完结 10 由 zeng 发布于 2025/4/25 14:01:53

DOI:10.1016/j.cell.2024.10.015
作者：Panrui Lu, Yalong Cheng, Lei Xue, Xintong Ren, Xilong Xu, Chenglong Chen, Longzhi Cao, Jiaojiao Li, Qingcui Wu, Shan Sun, Junjie Hou, Wei Jia, Wei Wang, Yan Ma, Zhaodi Jiang, Chao Li, Xiangbing Qi, Ni
文献类型：期刊论文
补充材料：只需要正文

Elsevier

Abstract：Targeted protein degradation (TPD) utilizes molecular glues or proteolysis-targeting chimeras (PROTACs) to eliminate disease-causing proteins by promoting their interaction with E3 ubiquitin

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