177Lu-labeled antibody-drug conjugate: a dual mechanistic treatment modality in solid tumors.

已完结 10 由胡天晔发布于 2025/3/29 15:48:13

DOI:10.1158/1535-7163.MCT-24-0254
作者：Aiko Yamaguchi,?Chisato M Yamazaki,?Yasuaki Anami,?Summer Y Y Ha,?Wei Xiong,?Robert T Ta,?Ningyan Zhang,?H Charles Manning,?Zhiqiang An,?Kyoji Tsuchikama
文献类型：期刊论文
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American Association for Cancer Research (AACR)

Abstract：To explore the potential of site-selectively radiolabeled antibody-drug conjugates (ADC) against solid tumors, we constructed and evaluated radiolabeled ADCs equipped with lutetium-177 (177L

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