Abstract 1312: Transcriptional signatures associated with lack of response to anti-PD-1 therapy in patients with renal cell carcinoma

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DOI:10.1158/1538-7445.AM2015-1312
作者：Maria Libera Ascierto, Tracee L. McMiller, Alan E. Berger, Robert A Anders, Chris Cheadle, Haiying Hu, Charles G. Drake, Drew M. Pardoll, Janis M. Taube, Suzanne L. Topalian
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American Association for Cancer Research (AACR)

Abstract：Background: The PD-1/PD-L1 immune checkpoint pathway limits host immune responses to cancer in the local tumor microenvironment. Monoclonal antibodies blocking PD-1 or PD-L1 have shown promi

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