Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system

已完结 10 由 1 发布于 2025/4/8 17:42:56

DOI:10.1038/s41563-024-02114-5
作者：Chang Wang, Yonger Xue, Tamara Markovic, Haoyuan Li, Siyu Wang, Yichen Zhong, Shi Du, Yuebao Zhang, Xucheng Hou, Yang Yu, Zhengwei Liu, Meng Tian, Diana D. Kang, Leiming Wang, Kaiyuan Guo, Dinglingge
文献类型：期刊论文
补充材料：只需要正文

Nature

Abstract：The systemic delivery of mRNA molecules to the central nervous system is challenging as they need to cross the blood–brain barrier (BBB) to reach into the brain. Here we design and synthesiz

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