Intravenous administration of blood–brain barrier-crossing conjugates facilitate biomacromolecule transport into central nervous system

已完结 10 由 1 发布于 2025/4/8 17:39:18

DOI:10.1038/s41587-024-02487-7
作者：Chang Wang, Siyu Wang, Yonger Xue, Yichen Zhong, Haoyuan Li, Xucheng Hou, Diana D. Kang, Zhengwei Liu, Meng Tian, Leiming Wang, Dinglingge Cao, Yang Yu, Jayce Liu, Xiaolin Cheng, Tamara Markovic, Alic
文献类型：期刊论文
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Nature

Abstract：Delivery of biomacromolecules to the central nervous system (CNS) remains challenging because of the restrictive nature of the blood–brain barrier (BBB). We developed a BBB-crossing conjugat

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