Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis.

已完结 10 由 LIMING 发布于 2025/6/9 19:26:30

DOI:10.1136/annrheumdis-2014-206517
作者：R F Schelbergen, E J Geven, M H J van den Bosch, H Eriksson, T Leanderson, T Vogl, J Roth, F A J van de Loo, M I Koenders, P M van der Kraan, W B van
文献类型：期刊论文
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Elsevier

Abstract：Objectives: Alarmins S100A8/A9 regulate pathology in experimental osteoarthritis (OA). Paquinimod is an immunomodulatory compound preventing S100A9 binding to TLR-4. We investigated the effe

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