Co-opting signalling molecules enables logic-gated control of CAR T cells

已完结 10 由 1 发布于 2025/6/8 17:55:01

DOI:10.1038/s41586-023-05778-2
作者：Aidan M. Tousley,?Maria Caterina Rotiroti,?Louai Labanieh,?Lea Wenting Rysavy,?Won-Ju Kim,?Caleb Lareau,?Elena Sotillo,?Evan W. Weber,?Skyler P. Rietberg,?Guillermo Nicolas Dalton,?Yajie Yin,?Dorota K
文献类型：期刊论文
补充材料：只需要正文

Nature

Abstract：Although chimeric antigen receptor (CAR) T cells have altered the treatment landscape for B cell malignancies, the risk of on-target, off-tumour toxicity has hampered their development for s

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