Centromeric DNA amplification triggered by viral proteins activates nuclear cGAS

已完结 10 由 AN 发布于 2025/6/11 12:46:43

DOI:10.1016/j.cell.2025.05.008
作者：Xavier Lahaye, Patrick Tran Van, Camellia Chakraborty, Anna Shmakova, Ngoc Tran Bich Cao, Hermine Ferran, Ouardia Ait-Mohamed, Mathieu Maurin, Joshua J. Waterfall, Benedikt B. Kaufer, Patrick Fischer,
文献类型：期刊论文
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Elsevier

Abstract：The cGAS-cGAMP-STING pathway is crucial for antiviral immunity. While cytosolic cGAS detects viral DNA, most DNA viruses shield their genome and invade the nucleus, where chromatin restricts

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