De Novo Discovery of a Noncovalent Cell-Penetrating Bicyclic Peptide Inhibitor Targeting SARS-CoV-2 Main Protease.

已完结 10 由 1 发布于 2025/6/16 16:41:50

DOI:10.1021/acs.jmedchem.4c01639
作者：Yahong Tan, Jinyue Yang, Min Wang, Qi Peng, Yongqi Li, Lifeng Fu, Mengmeng Zhang, Jiang Wu, Guanya Yang, Christopher John Hipolito, Youming Zhang,&nbs
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Macrocyclic peptides have garnered significant attention as promising drug candidates. However, they typically face challenges in achieving and enhancing cell permeability for access to intr

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