Synthesis and evaluation of neuroactive steroids with novel pharmacophore at C-21 let identify a compound with advantageous PK profile and higher EC50 and Emax as PAM on GABAA receptor

DOI:10.1016/j.ejmech.2024.116602
作者：Mingxu Ma ,?Hengwei Xu ,?Liang Ye ,?Chunmei Li ,?Haibo Zhu ,?Wanglin Jiang ,?Wenyan Wang ,?Huijie Yang ,?Yingjie Yang ,?Yao Wang ,?Jingwei Tian
文献类型：期刊论文
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