Early Process Development of PF-07054894, a Squaramide-Based Antagonist of C–C Chemokine Receptor Type 6 (CCR6)

已完结 10 由俊_ 发布于 2025/5/22 10:01:45

DOI:10.1021/acs.oprd.3c00451
作者：Gary M. Chinigo*,?Emma L. McInturff*,?Scott W. Bagley,?Richard W. Barnhart,?David C. Blakemore,?Lu Han,?Taegyo Lee,?Javier Magano,?J. Christopher McWilliams,?Sebastien Monfette,?James J. Mousseau,?Sen
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：The original synthesis of a CCR6 antagonist and subsequent enablement for kilogram manufacture is presented. Highlighted improvements made in the preparation for the scale-up campaign includ

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