Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging

已完结 10 由 Emily 发布于 2025/5/28 0:51:55

DOI:10.1038/s41594-023-01163-9
作者：Rui Guo, Jianping Liu, Xia Min, Wen Zeng, Bing Shan, Mengmeng Zhang, Zhuohao He, Yaoyang Zhang, Kaiwen He, Junying Yuan, Daichao Xu
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1038/s41594-023-01163-9

Nature

Abstract：Autophagy is a lysosome-dependent degradation pathway essential for cellular homeostasis, which decreases with age. However, it is unclear how aging induces autophagy decline. Here we show t

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