Poly(carboxybetaine) lipids enhance mRNA therapeutics efficacy and reduce their immunogenicity

已完结 10 由 Direction92 发布于 2025/6/3 15:17:36

DOI:10.1038/s41563-025-02240-8
作者：Sijin Luozhong, Pingchuan Liu, Ruoxin Li, Zhefan Yuan, Erica Debley, Yu Chen, Yuping Hu, Zeyu Cao, Meng Cui, Kay McIlhenny, Caleb McCurdy, Dani Bhashyam, Stephan Wilkens, Prince Zhang, Austin Kwan, Ma
文献类型：期刊论文
补充材料：只需要正文

Nature

Abstract：Messenger RNA (mRNA) therapeutics are a promising strategy to combat diverse diseases. Traditional lipid nanoparticle (LNP) formulations for mRNA delivery contain poly(ethylene) glycol (PEG)

应助信息

求助已完结，文件已删除 如有需求请重新发布求助一键发布

感谢使用Book学术
本站所有文献仅供个人学习和参考，请勿将文件进行传播。共同遵守网站规定和相关知识产权规定。

上一个求助:其它数据库Naturally Fractured Carbonate Reservoir Characterization: A Case Study of a Mature High-Pour Point Oil Field in Hungary 下一个求助:Royal Society of Chemistry (RSC)Advances in solar-driven, electro/photoelectrochemical, and microwave-assisted upcycling of waste polyesters