Inhibition of toll-like receptor 4 by allicin suppresses mitochondrial DNA-mediated inflammation and pyroptosis to alleviate myocardial ischemia-reperfusion injury.

待确认 10 由科研民工发布于 2026/7/11 16:30:48

DOI:10.1016/j.phymed.2026.158513
作者：Shichao Liang,?Song Wu,?Jiajie Yin,?Tong Gao,?Mengru Liu,?Yijie Gao,?Fangyuan Luo,?Danni Wu,?Songyuan Yu,?Lin Zhao,?Baofu Wang,?Xianlun Li
文献类型：期刊论文
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Elsevier

Abstract：Background: Mitochondrial DNA (mtDNA) leakage after myocardial ischemia/reperfusion (MI/R) injury activates inflammation and pyroptosis. Although toll-like receptor 4 (TLR4) is a known media

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