ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D

已完结 10 由柳絮发布于 2025/1/10 11:51:08

DOI:10.1038/s41586-024-07373-5
作者：Gang Du,?Liam B. Healy,?Liron David,?Caitlin Walker,?Tarick J. El-Baba,?Corinne A. Lutomski,?Byoungsook Goh,?Bowen Gu,?Xiong Pi,?Pascal Devant,?Pietro Fontana,?Ying Dong,?Xiyu Ma,?Rui Miao,?Arumugam B
文献类型：期刊论文
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Nature

Abstract：Gasdermin D (GSDMD) is the common effector for cytokine secretion and pyroptosis downstream of inflammasome activation and was previously shown to form large transmembrane pores after cleava

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