A clinical-stage Nrf2 activator suppresses osteoclast differentiation via the iron-ornithine axis

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DOI:10.1016/j.cmet.2024.03.005
作者：Yimin Dong, Honglei Kang, Renpeng Peng, Zheming Liu, Fuben Liao, Shi-an Hu, Weizhong Ding, Pengju Wang, Pengchao Yang, Meipeng Zhu, Sibo Wang, Minglong Wu, Dawei Ye, Xin Gan, Feng Li, Kehan Song
文献类型：期刊论文
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Elsevier

Abstract：Activating Nrf2 by small molecules is a promising strategy to treat postmenopausal osteoporosis. However, there is currently no Nrf2 activator approved for treating chronic diseases, and the

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