Site-Specific Modification of Native IgGs with Flexible Drug-Load.

已完结 10 由小钱发布于 2025/1/14 12:21:52

DOI:10.1002/cbic.202400511
作者：J?ri E Wehrmüller,?Julia C Frei,?Torsten Hechler,?Michael Kulke,?Andreas Pahl,?Martin Béhé,?Roger Schibli,?Philipp R Spycher
文献类型：期刊论文
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Abstract：Homogeneous, site-specifically conjugated antibodies have shown to result in antibody-drug conjugates (ADCs) with improved efficacy and tolerability compared to stochastically conjugated ADC

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